Your chronological age is on your passport. Your biological age measures how well your cells function compared to the average person your age. The gap can be substantial.
Epigenetic Clocks
The most promising method is epigenetic clocks — algorithms that analyse DNA methylation to estimate biological age. The Horvath clock predicts biological age from any tissue with remarkable accuracy.
People whose biological age was 5+ years younger than their chronological age had significantly lower risk of heart disease, cancer and early death.
Regular aerobic exercise, Mediterranean diets, quality sleep and social connection all show associations with younger biological age. Your chronological age is fixed — your biological age is malleable.